When close is not close enough: a comparison of endogenous and recombinant biomarker stability samples

Dr Stephanie Fraser is an Associate Research Fellow in the Pharmocokinetics, Dynamics and Metabolism department at Pfizer, Groton, Connecticut. Since 2010 she has led a small but ambitious group of scientists that provide ligand-binding and immunoassay-based support to clinical biomarker programs across multiple therapeutic areas. Prior to joining Pfizer, Stephanie spent 5 years in preclinical toxicology at Charles River Laboratories where she managed a flow cytometry laboratory. She received her PhD in cellular and molecular biology from the University of Nevada, Reno in 1999 and has since focused on biomarker development and fit-for-purpose bioanalytical assays. Stability for biomarker assays should...