The current status of single-cell proteomics for biomedical research

Single-cell proteomics, Biomedical research in drug response, Multi-omics analysis, Proteomics in human adaptation, Bioanalytical science techniques, Single-cell mouse models in drug research, Human drug response studies, Proteomic profiling in biomedical research, Single-cell analysis in drug adaptation, Advanced bioanalytical methods, Proteomics for drug response, Single-cell proteomics in human biology, Multi-omics in biomedical research, Bioanalytical science in proteomics, Mouse models for single-cell analysis, Drug response and single-cell proteomics, Human adaptation through proteomics, Proteomics in drug development

Wednesday 21 August 2024
07:00 [PST]  10:00 [EST]  15:00 [BST]
Alternative time zones

 

An update on the current status of single-cell proteomics as applied to human drug response and adaptation.

Single-cell proteomics has been a flashy new technology and approach for some years now. For the last 4 years, our group has endeavored to utilize single-cell proteomics to better understand how human cells respond to and adapt to drug treatments. This webinar will provide an overview of the challenges we’ve encountered, and some examples of where we’ve succeeded. We’ll begin with our controversial decision to use the instruments we had for multiplexed analysis and we’ll work through our even more controversial identification of protein post-translational modifications in single human cells. The final part of the webinar will focus on our work — and new challenges — in single cells derived from mouse models.

REGISTER NOWWhat will you learn?Who may this interest?Speaker


What will you learn?

  • The basics of single-cell proteomics
  • The current state of single-cell proteomics as of the date of this talk
  • The challenges and triumphs of single-cell proteomics in human cells
  • The ongoing work on single-cell mouse models

Who this may interest?

  • Bioanalytical scientists interested in single-cell multi-omics or pharmacology
  • Bioanalytical scientists in the field of proteomics/multi-omics

Speaker:

Benjamin C. Orsburn
Principal Investigator
John Hopkins University (MD, USA)

Ben is an established expert in translational mass spectrometry, most recently as a Principal Investigator at the Johns Hopkins University School of Medicine. His research is centered on applying high-throughput and single-cell proteomics/multi-omics as tools to understand heterogeneity in drug response and adaptation. He is best known for his attempts to make proteomics accessible to a wide audience through the News In Proteomics                                                                   Research blog and the US Human Proteomics Organization-sponsored                                                                           podcast, THE Proteomics  show. Ben is also the winner of our 2023 of the                                                                           BOSCA Award.