Glycomics and glycoproteomics: A (not so) new frontier in biology

Glycosylation is the most abundant and complex post-translational modification and is increasingly being recognized as playing a key role in health and disease.

Protein glycosylation is the most common and most complex post-translational modification, with sugar moieties being attached to proteins, thus exponentially  increasing proteomic diversity. It is critical for a broad range of biological processes and functions, including protein folding, stability, cell attachment and cell-cell-signaling. Glycosylation also plays important roles in disease development, with aberrant glycosylation linked to neoplastic, metabolic, neurodegenerative and other disorders. Recent progress in analytical technologies, prominently based on mass spectrometry, is currently leading to renewed interest and important new insights in this long somewhat neglected, crucial domain of biology.

 

What will you learn?Who may this interest?Speakers
  • Basics of carbohydrate biology
  • Prevalence and complexity of protein glycosylation
  • Challenges and opportunities of glycoproteomics research
  • New technologies facilitating glycoproteomics research
  • Biomedical scientists in academia and industry
  • Students

Speakers

  Klaus Lindpaintner, MD, MPH

VP, Glycobiology Solutions

Bruker Scientific LLC (MA, USA)

Klaus Lindpaintner, MD, MPH, FACP, is the incoming VP of Glycobiology Solutions at Bruker. He previously held senior positions at Pfizer (MA, USA) as Senior VP and Global Head, Human Genetics and Computational Biomedicine (MA, USA) as Senior VP and Director, Roche Center for Medical Genomics (MA, USA), Thermo Fisher Scientific (MA, USA) as CSO, InterVenn Bioscience (CA, USA) as CSO/CMO and part of the faculty at Harvard Medical School (MA, USA). Klaus has co-authored some 250 scientific papers and holds honorary and adjunct professorships at several academic institutions. He serves on numerous boards, working groups and advisory panels on issues related to the successful implementation of novel technologies in precision medicine.

 

 

In association with

 

This webinar was recorded on Wednesday 13 December 2023