Generation of recombinant tool antibodies to support cell and gene therapy development
Highly specialized antibodies are required for cellular kinetics and bioanalytical assays supporting cell and gene therapy development. These antibodies are difficult to generate utilizing animal immunization, and are prone to variability between batches and inconsistent supply.
Bio-Rad custom antibody experts have developed recombinant antibodies against chimeric antigen receptors and transgene products utilizing a process that combines antibody phage display with SpyTag technology. Applying these powerful technologies enables the production of antibodies in multiple formats in under 3 months and offers a range of options for site-directed conjugation. These highly specific, well-characterized antibody reagents are sequence defined, guaranteeing a secure supply throughout the assay lifecycle.
What will you learn?
- How in vitro antibody selection strategies can meet challenging specificity requirements
- What SpyTag technology is and how it is utilized with Bio-Rad’s recombinant antibodies
- How SpyTag enables site-directed conjugation and rapid assembly of different antibody formats
Who may this interest?
This webinar is recommended for scientists seeking a rapid service for the generation of custom antibody reagents designed to target a chimeric antigen receptor, transgene product or large molecule biologic, for use in bioanalytical assays.
Speaker
Paul Royle
Technical Sales Manager Custom Antibodies
Bio-Rad Laboratories
Paul Royle is the Technical Sales Manager for Bio-Rad’s Custom Antibody Service and has been with Bio-Rad’s antibody division for over 8 years. Prior to this he worked in an immunology diagnostics company for almost 7 years. Paul holds a degree and PhD from the University of Nottingham (UK), and has postdoctoral research experience from the University of Warwick (UK).
In association with
