Bioanalytical applications of inductively coupled plasma mass spectrometer (ICP-MS)
Inductively coupled plasma mass spectrometry (ICP−MS) is an analytical technique used to measure elements at trace levels in biological fluids. The key part of ionization in ICP−MS is a set of concentric (torch) tubes partly surrounded by a radio-frequency induction coil. When argon gas flow is introduced through the outmost torch tubes, the gas can be turned into plasma with briefly discharged electrons and the radio-frequency magnetic field of the induction coil. At high temperatures, the analyte introduced through the plasma by the central tube will be atomized and ionized, and captured by the mass analyzer of the ICP−MS. In this webinar, you will learn how ICP−MS works in ionization and removal of polyatomic interferences, and the sample preparation approaches in bioanalysis by ICP-MS.
What will you learn?
- The principle and technology behind ICP−MS
- How ICP−MS can find the quantity of metallic or metalloid elements
- Applications of ICP−MS
- How samples are prepared in ICP−MS bioanalysis
- Examples of case studies of ICP−MS bioanalysis
Who may this interest?
- Clinical trial labs and managers
- Preclinical drug testing labs
- Toxicology and safety assessment labs and managers
- Pharmacokinetics labs
- Nanoparticle labs
Speaker
Dr Changming Yang
Senior Director of Small Molecule Team for International Projects, Bioanalytical Services Department
WuXi AppTec – Lab Testing Division (Shanghai, China)
Dr Changming Yang is currently Senior Director in the Bioanalytical Services (BAS) Department, Lab Testing Division, WuXi (Shanghai, China) Co., Ltd. He obtained his BSc in chemistry from Nanjing University (China) and his PhD in analytical chemistry from Oklahoma State University (OK, USA). Dr Yang has close to 20 years of industrial experiences of analytical chemistry techniques (e.g., capillary electrophoresis, HPLC, LC−MS/MS and ICP−MS) applied in ISO/GMP/GLP regulated systems. He is the first inventor of US patent (Patent #: US 8399829). He joined BAS at WuXi AppTec in September 2016 and is leading the small molecule international team to support global clients in their preclinical and clinical studies.
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