Watch the AB SCIEX Pharma & Biologics Webinar Series from August 21-December 4, 2013
AB SCIEX Pharma & Biologics Webinar Series from August 21-December 4, 2013, All webinars are at 11:00 AM Eastern / 8:00 AM Pacific
View previous webinars from the series
Peptide Quantification on the QTRAP® Mass Spectrometers with microflowLC: Bridging the Best of Small Molecule and Proteomics Analyses
View the webinar and learn:
• Protein and peptide quant method building and optimization using MIDAS strategy on QTRAP® instrument
• Benefits of going microflow LC for peptide quant assay
• Alternate MS techniques to reduce background noise such as MRM3 and SelexIONTM ion mobility technique
Speaker:
Carmen Fernández-Metzler, Ph.D., President, PharmaCadence Analytical Services, LLC
An Advance Look At BioPharmaView™ Beta Software: the Next Generation Integrated Software Solution for Comprehensive Analysis of Biologics
View the webinar and learn:
• How BioPharmaView™ software can streamline and automate your analysis of intact and digested biotherapeutics
• How to get a complimentary Beta evaluation copy of the software
• To provide feedback on how we can continue to evolve the product to best suit your needs
Speaker:
Justin Blethrow, Technical Marketing Manager, Biologics, AB SCIEX
Challenges and Practical Solutions in Large Molecule Quantification by LC-MS
View the webinar and learn:
• When to choose LBA vs. LCMS assay for large molecule bioanalysis
• Key advantages of choosing LCMS for biotherapeutics quantification
• How to increase sensitivity and selectivity of your assay by choosing the right MS technology: HRMS vs. Triple Quad
Speaker:
Fabio Garofolo, Vice-President of Bioanalytical Services, Algorithme Pharma Inc.
Optimizing High-Throughput LC/MS/MS Bioanalysis in Drug Discovery
View the webinar and learn:
• About using DiscoveryQuant™ software for the automation of method development, acquisition and processing
• Discovery strategies for integrated quant/qual workflows using TripleTOF® and QTRAP® analyzers
• Advantages of using enterprise-wide tools across the entire drug discovery and development pipeline
Speaker:
Brendon Kapinos, Senior Associate Scientist, Pfizer
Host Cell Protein Analysis: Rapid Detection of Low PPM Level Host Cell Proteins Using the TripleTOF® 5600+ System and SWATH™ Acquisition Technology
View the webinar and learn:
• How mass spectrometry can provide a superior, unbiased alternative to ELISA-based Host Cell Protein quantitation assays for biotherapeutics
• How TripleTOF® instruments can provide low PPM level detection and quantitation of Host Cell Proteins in less than an hour
• How the unique SWATH™ Acquisition mode can provide a one-method solution for comprehensive characterization of your biotherapeutic – including PTM analysis and host cell protein detection and quantitation-while minimizing method development and run-to-run variation
Speaker:
Eric Johansen, Senior Application Scientist & Global Lead Scientist, BioPharma Applications, AB SCIEX
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High Throughput Data Independent Approach for Qualitative and Quantitative Lipidomic Analysis
View the webinar and learn:
• To describe the concept of data independent analysis – termed MS/MSALL with SWATH™ Acquisition – in application to the quantitative analysis of lipids in complex biological extracts
• To discuss quantitative approaches using proper internal standards for quantitative lipid profiling
• To provide a complete workflow and analytical platform for lipidomics with automated data processing and results reporting using LipidView™ software and MultiQuant™ software in high throughput settings
Speaker:
Michael Kiebish, Ph.D., Senior Scientist, Berg Diagnostics
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High Throughput Metabolite ID: Are We There Yet?
View the webinar and learn:
• Data dependent and data independent (SWATH™) acquisition strategies for high efficiency data acquisition
• Reactive metabolite screening made easy
• Data processing software algorithms (PCVG) and workflows for metabolite identification
Speaker:
Natasha Penner, Ph.D., Senior Scientist, Biogen Idec
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Combining Selectivity and Sensitivity for Targeted Peptide Quantitation
23rd October 2013 11:00 am EDT 8.00 PDT
In this webinar, you will learn:
• How to combine orthogonal selectivity with the extreme performance of the QTRAP® 6500 system
• The many benefits of MRM3 and the SelexION™ differential mobility interface
• How offline sample preps can be used in your workflows to increase sensitivity throughput and robustness
Speakers:
Loren Olson, Technical Marketing Manager, Pharma Applications, AB SCIEX
Mike McGinley, Product Manager, Phenomenex Inc
Comparison of MS/MSall with SWATH™ vs. Information-Dependent Acquisition HRMS Methods for Metabolite Identification
6th November 11:00 EDT 08.00 PDT
In this webinar, you will learn:
• Advantages of SWATH™ data acquisition for HT metabolite ID
• Simplifying soft spot analysis using isotope pattern in MS/MS spectrum with SWATH™ acquisition
• Novel data mining algorithms for metabolite ID
Speaker:
Rick Schneider, Sr. Principal Scientist, Pfizer
Biotransformation of Antibody-Drug Conjugates: Current Perspective and Analytical Approaches
20th November 2013 11:00 EDT 08.00 PDT
In this webinar, you will learn:
• The unique challenges involved in analysis of biotransformations of antibody-drug conjugates
• Analytical strategies and rationale employed in real-world case studies
• How knowledge gained through characterization studies can be used to guide development of effective quantitative bioanalytical strategies.
Speaker:
Keyang Xu, Senior Scientist, Genentech
SWATH-based Pharmacokinetic Quantification to Increase Selectivity, Specificity and Signal-to-Noise Ratio with the Benefits of Non-Targeted Approach on UHPLC-HRMS
4th December2013 11:00 EDT 08.00 PDT
In this webinar, you will learn:
• Advantages of UPLC based integrated quant/qual workflow for bioanalysis
• SWATH™ data independent acquisition for integrated quant/qual assay in drug discovery and development
• Advanced quantification strategies like MRMHR, SWATH™ acquisition, and TOF MS for increased sensitivity and selectivity using HRMS
Speaker:
Ragu Ramanathan, Ph.D., Director of Biotransformation and Bioanalytical DMPK, QPS Delaware
