Active drug quantification by hybrid LC–MS: an interview with Roland Staack & Gregor Jordan

In this interview, Roland Staack and Gregor Jordan from Roche (Basel, Switzerland) talk about their recent publication, ‘Evaluation of the potential use of hybrid LC–MS/MS for active drug quantification applying the free analyte QC concept’, explaining the advantages and challenges of using hybrid LC–MS/MS methods, as well as predicting the future of the development of appropriate extraction conditions for correct active drug quantification by hybrid LC–MS/MS.

Interested in hybrid LC–MS/MS? Check out their article on Free analyte QC concept: a novel approach to prove correct quantification of free therapeutic protein drug/biomarker concentrations