Technology Digest: Transforming drug development with label-free, kinetic-based assays
Ligand-binding assays (LBAs) are kinetic-based assays widely used to measure interactions between two molecules, such as proteins, antibodies and many others. They are considered the industry ‘gold standard’ for protein-protein interaction analysis as well as protein quantification due to their high sensitivity, selectivity and throughput capabilities. The development and validation of LBAs are critical to drug production as they ensure safety and efficacy standards are maintained. In this Tech Digest, we explore assay development and validation for kinetic-based assays and how these assays can be achieved on the Octet® BLI platform.
This eBook includes:
- TECHNOLOGY DIGEST: Transforming drug development with label-free, kinetic-based assays
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APPLICATION GUIDE: Ligand binding assays that meet compliance with Octet® BLI systems
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WHITE PAPER: Enhanced productivity and labor efficiency in lot release and in-process testing of biologics in GxP laboratories
- APPLICATION NOTE: Octet® potency assay: development, qualification and validation strategies
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