Merck: New SOLu -Trypsin Enzyme Brings Stability to Mass Spectrometry

MilliporeSigma’s Advanced Proteomics Grade SOLu-Trypsin is an exclusive, solution stable enzyme for mass spectrometry. Designed to be stable in solution when refrigerated, SOLu-Trypsin can be used immediately without preparation. Other forms of trypsin require thawing or reconstitution, and must be discarded if not used immediately. SOLu-Trypsin allows excess product to be saved for future use, thus eliminating unnecessary waste and cost.  SOLu-Trypsin is formulated with a high-purity recombinant trypsin, free of chymotryptic activity, to ensure high fidelity digestion.

Key benefits of SOLu-Trypsin include:

  • Ready to use—no preparation, such as reconstitution or thawing, is required
  • Fits seamlessly into established workflow—no need to modify protocols
  • Eliminates waste—remains stable in the refrigerator after use so there is no need to discard excess product
  • Recombinant, porcine sequence—no chymotryptic activity
  • Stable for short-term use at room temperature in an autosampler or on a liquid handling robot

The SOLu-Trypsin enzyme builds on MilliporeSigma’s innovative portfolio of products for large molecule mass spectrometry.

Learn more about SOLu-Trypsin at SigmaAldrich.com/solu-trypsin


Application Notes for SOLu-Trypsin

Evaluation of Recombinant, Chemically Treated Trypsin in Proteomics and Protein Characterization Assays