Merck: Ascentis® Express Products: Columns used for seperation of peptides, amines and small proteins

Peptide ES-C18 HPLC Columns

Ascentis® Express Peptide ES-C18 is a high-speed, high-performance liquid chromatography column based on a new 160Å Fused-Core® particle design. As such, Ascentis Express Peptide ES-C18 columns were specifically engineered to separate higher molecular weight compounds; peptides and small proteins for example. Their capacity for larger analytes and exceptional ruggedness make them ideal for proteomic applications like peptide mapping, as well as oligonucleotide analysis.

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RP-Amide HPLC Columns

While the Ascentis® Express C8 and C18 provide classic reversed-phase selectivity, the RP-Amide phase provides alternate reversed-phase selectivity, improved peak shape for bases, 100% aqueous compatibility, and LC-MS compatibility, to our high speed HPLC column line based on Fused-Core® particle technology. Ascentis Express RP-Amide provides increased selectivity for polar compounds, especially those that can act as a hydrogen bond donor.

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To download an article about the RP-Amide column or general seperation of amines please click the links below

Synthetic Cannabinoid Analysis – Standards & Methods: To download the full article click here
Derivatization and Separation of Aliphatic Amines: To download the full article click here