Preanalytics: what can metabolomics learn from clinical chemistry?

“After blood drawing the metabolism of billions of red and white blood cells as well as of platelets is still active resulting in the uptake and release of metabolites, thereby altering the metabolite profile in the sample tube.” The analytical quality in metabolomics projects is of utmost importance as a guarantor for reliable results and accordingly for the success of the entire project. However, the highest analytical quality employing the most sophisticated instruments is in vain if the sample quality is poor. This means that in addition to the analytical performance the major key for the success of metabolomics projects...