Microfluidic homo- and hetero-geneous immunoassays: a tool to accelerate protein biomarker development

“Through integration, multiplexing, speed and automation, microfluidic immunoassays have the potential to create a paradigm shift in biomarker development.” Molecular biomarkers have the potential to change the face of medicine. The ability to identify patients who will respond to therapy, diagnose illness earlier and more accurately, and understand the underlying biochemical mechanisms of disease, would have tangible impacts on human health. As the executers of molecular function and mediators of virtually every process that takes place in the body, protein biomarkers in particular have tremendous predictive and prognostic value. Yet, while hundreds of thousands of articles have been published touting...