Metabolic profiling in the arena of gut–brain interaction studies for Alzheimer’s disease

O Deda & H G Gika  | Bioanalysis, 12(8), 501-504 (2020) Keywords: • Alzheimer’s disease • gut–brain interaction • metabolic profiling • metabolites Since 400 BC, Hippocrates theorized that ‘bad digestion is the root of all evil’, while from the dawn of the twentieth century, Elie Metchnikoff, winner of the Nobel Prize speculated that gut microbiome manipulation with host-friendly bacteria, like those found in yogurt could prove to be the ‘elixir’ of long life. Recent technological advantages highlighted the impact of gut microbiome on human health and facilitated the emergence of these concepts as core research fields. The scientific community nowadays characterizes this large reservoir of...