In the Zone: immunogenicity
INFOGRAPHIC| PODCAST | RESOURCES
Pathogen immunity has long been determined by antibody-detection assays, however, in many situations, measuring T-cell immunity to specific pathogens can provide physicians with significantly improved clinical utility. Monitoring T-cell immunity is also critical in the development of new therapies as mechanism to assess immunogenicity. T-cell immunity can be measured with a variety of different techniques, each demanding a certain level of expertise, equipment and labor intensity.
In this feature, we explore the key qualities to look for to ensure success when outsourcing immunogenicity assay development and testing. We also explore the methods for – and challenges involved with – T-cell immunity monitoring and assay development.
PODCAST
T-cell immunity monitoring and assay development: an interview with Steven Kleiboeker
Ahead of his presentation at the World Vaccine and Immunotherapy Congress (2–5 December, San Francisco; CA, USA), Dr Steven Kleiboeker (Vice-President of Research and Development at Viracor Eurofins BioPharma Services, Kansas City, MO, USA) discusses the methods for – and challenges involved with – T-cell immunity monitoring and assay development. He also discusses the current research focuses at Viracor Eurofins laboratories, the importance of other viral assays and his hopes for the future directions of T-cell immunity assays.
INFOGRAPHIC
Key qualities to ensure success when outsourcing immunogenicity assay development
This infographic highlights the key qualities to look for in a CRO to ensure the best results when outsourcing immunogenicity assay development and testing.
RESOURCES
Susceptible or immune? CMV T-cell immunity accurately predicts patient status
