Drug detection in biological specimens: recent colorimetric methods

Recently, the detection approaches based on the metal nanoparticles (NPs) have attracted more and more attention due to their great extinction coefficient and strong surface plasma resonance properties. This report focuses on the present status of drug detection with metal NPs as ultrasmall labels in colorimetric-based methods. Although progresses have been emerged in drug detection, much work remains to be done to overcome the great challenges on sample preparation of complicated biological fluids. Plasmonic NPs can be combined with other existing functional groups to produce frameworks with novel multifunctional surface plasmon resonance for generating optical platform in drug detection. With their...