Current biosensor technologies for rapid point-of-care diagnosis of neonatal sepsis

Neonatal sepsis is a leading cause of global infant mortality and is especially prevalent in countries where many births occur in unsanitary conditions. Early diagnosis of neonatal sepsis and identification of the underlying infection are critical in determining the most effective course of treatment and reducing mortality. Sepsis is a severe immune reaction that occurs in response to an infection, which can damage bodily tissues and cause multiple organ failure, even death, if left untreated. Guidelines suggest that treatment should begin as soon as possible, with broad spectrum antibiotics administered within 3 hours of identification of suspected sepsis. Blood cultures...