Cosmetic bioanalysis using LC-MS: challenges and future outlook

“This review will focus on the challenge and future perspective of cosmetic bioanalysis by LC–MS techniques including targeted analysis, non-targeted analysis, matrix effects, carryover, and method validation.” Cosmetic products are used on their skin, hair, nails and teeth on a daily basis by many consumers. The world cosmetics market reached US$325 billion in 2011 and is growing at approximately 3% per year [1]. Therefore, safety of cosmetic products is a serious international concern. The main ingredients of cosmetics include acids, preservatives, oils, surfactants, moisturizing agents, emulsifiers, hair dyes, pigments and fragrances. The analysis of cosmetic ingredients in biological matrix is...