Bioimaging of elements and small molecules using MS

“Given the unique and varied capabilities of MS imaging, it is perhaps surprising that it has not been more broadly accepted in biological and biomedical laboratories.” MS has undoubtedly gained a pre-eminent position in the bioanalytical toolbox. Whether in combination with chromatographic methods such as LC or GC or as a standalone technique, MS is universally accepted and applied in a wide range of bioanalytical situations. This is primarily due to the high sensitivity and specificity of the technique and the broad range of analytes that can be targeted. GC–MS and LC–MS are standard techniques for the analysis of drugs...