Bioanalysis volume 10, issue 3

Issue 3 of Bioanalysis volume 10 is now available. This issue includes a commentary on drug detection in biological specimens, a methodology on offline derivatization LC–MS/MS and a review on the principles of vaccine potency assays.

Research article
Pharmacokinetic determination and analysis of nortriptyline based on GC–MS coupled with hollow-fiber drop-to-drop solvent microextraction technique

Commentary
Drug detection in biological specimens: recent colorimetric methods

Interested in drug detection? Read our article on tissue analysis – a powerful tool for drug discovery and development.

Methodology
Offline derivatization LC–MS/MS method for simultaneous estimation of vanillin and vanillic acid in guinea pig plasma

Special Report
Extended 3D and 4D cumulative plots for evaluation of unmatched incurred sample reanalysis

Review
Principles of vaccine potency assays

Emerging technologies for biotherapeutic bioanalysis from a high-throughput and multiplexing perspective: insights from an AAPS emerging technology action program committee