Bioanalysis and the oncology revolution

Wickremsinhe E & James C | Bioanalysis, 13(4), 291-294, (2021) Keywords: • bioanalytical • co-med interference • co-med stability • novel drug modalities • oncology studies • polypharmacy • selectivity • stability testing Major advances continue to be made in oncology driven by an increasing understanding of cancer biology and genetics. The last decade has seen treatment successes with immuno-oncology drugs which join classical cytotoxic drugs and molecularly targeted agents as a third paradigm in oncology drug treatment [1]. In 2018 over 25% of all new drug registrations were in oncology [2] and they include an increasing number of monoclonal...