Approaches to overcome the challenge of sample stability for flow cytometry analysis in clinical trials

A Hays | Bioanalysis, 13(21), 1587-1589 (2021) Keywords: • biomarkers • cell fixation • clinical trials • flow cytometry • sample stability Flow cytometry is a technology that has been increasingly valuable in support of biomarker analysis for clinical trials. It has many clinical applications including the ability to provide data to support safety or exploratory studies by utilizing basic or complex immunophenotyping, pharmacokinetic, receptor occupancy, target engagement, cell activation, functional and intracellular expression assays. The assays on this platform often provide important data in support of clinical trials, and thus it is important to ensure the data generated is...