Application note: Robustness Evaluation of ekspert™ microLC 200 system in the Quantitation of Drugs in Hydrolyzed Urine (AB SCIEX)
The interest in microflow UHPLC for quantitation is increasing due to its ability to improve the throughput and sensitivity while reducing costs and instrument maintenance intervals.
Historically, microflow UHPLC has been overlooked in the development of LC/MS/MS methods which involve challenging sample matrices because of robustness issues. The ekspert microLC 200 is specifically designed to provide reliable and robust performance typically associated with 2.1 mm ID column based analytical separations.
This application note presents the results of a long term robustness study using the ekspert microLC 200 and AB SCIEX QTRAP® 5500 for the quantitation of drugs in hydrolyzed urine.
