An evolutionary view of chromatography data systems used in bioanalysis

"In four decades there have been major changes from a simple chart recorder output... through simple automation of peak measurement, calculation of standard curves and quality control values and instrument control to the networked chromatography data systems of today..." The evolution of chromatography data systems (CDSs) used in bioanalysis over four decades is reviewed from the personal perspective of the author. The approach will be selective and therefore not all techniques and approaches will be included or discussed. In this paper I will use the term CDS to include (incorrectly) manual methods of peak measurement to ensure complete coverage of...