Case study: automating ELISA-based assays to assess the purity of therapeutic viral vectors
In this case study, the analytical development group at AGC Biologics (Milan, Italy) describes the automation of two ELISA-based workflows to assess lentiviral vector purity, using a Hamilton Microlab® STARlet liquid handler integrated with a plate washer, a plate spectrometer and two plate incubators.
Highlights of this case study:
- Overview of the analytical methods automated by AGC Biologics Milan on Hamilton liquid handlers
- Detailed description of two ELISA-based automated workflows to assess the purity of the lentiviral vectors: residual benzonase and residual host-cell proteins
- Advantages of the Hamilton VENUS Scheduler to plan and execute parallel assays using the same sample aliquot
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